v. t. [ Pref. dis- + acquaint: cf. OF. desacointier. ] To render unacquainted; to make unfamiliar. [ Obs. ] [ 1913 Webster ]

While my sick heart
With dismal smart
Is disacquainted never. Herrick. [ 1913 Webster ]

n. Neglect of disuse of familiarity, or familiar acquaintance. [ Obs. ] South. [ 1913 Webster ]